Cough {middle dot} 3: Chronic cough and gastro-oesophageal reflux
نویسندگان
چکیده
منابع مشابه
Cough. 3: chronic cough and gastro-oesophageal reflux.
The pathogenesis and clinical features of gastro-oesophageal reflux related cough are complex and the diagnostic tests available are of limited reliability. Treatment needs to be tailored to the specific needs of individual patients and other possible causes of chronic cough should be investigated. Treatment should only be considered to have failed when cough persists after administration of pr...
متن کاملChronic cough and gastro-oesophageal reflux.
In their in-depth review of chronic cough and gastro-oesophageal reflux (GOR), Fontana and Pistolesi suggest that proton pump inhibitors are the most effective treatment for GOR related cough. However, most studies evaluating the efficacy of proton pump inhibitors are not placebo controlled and do not use objective markers of cough severity to assess treatment responses. We are aware of two dou...
متن کاملGastro-oesophageal reflux and cough.
Gastro-oesophageal reflux, either singly or in association with postnasal drip and/or asthma is considered to be a cause of chronic cough. The amount and nature of gastro-oesophageal reflux however is often normal with acid suppression having very little, if any therapeutic effect in these patients. This review examines the challenges posed when exploring the reflux-cough link, and discusses th...
متن کاملGastro-oesophageal reflux and tachykinins in asthma and chronic cough.
more frequent in severe asthma. Despite these unavoidable limitations, the report by Qiu et al is important because it promotes a better understanding of the events contributing to the development of severe exacerbations. Indeed, this study provides the framework for the cellular changes occurring in the airway tissue and the molecular mechanisms responsible for inflammatory cell recruitment. A...
متن کاملCHRONIC COUGH Patients with gastro-oesophageal reflux disease and cough have impaired laryngopharyngeal mechanosensitivity
Background: Laryngopharyngeal sensitivity (LPS) is important in preventing pulmonary aspiration and may be impaired by anaesthesia and stroke. It has been suggested that gastro-oesophageal reflux disease (GORD) may also impair LPS, although the underlying mechanism is unclear. The aim of this study was to compare LPS in patients with chronic cough and GORD with healthy subjects and to determine...
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ژورنال
عنوان ژورنال: Thorax
سال: 2003
ISSN: 0040-6376
DOI: 10.1136/thorax.58.12.1092